Catalytic antibodies have attracted attention because they can combine exquisite specificity with permanent and potent antigen inactivation. The field has enjoyed a renaissance in recent years due to the discovery of antibodies with comparatively efficient peptidase and nuclease activities. In principle, antibody catalysis could serve as a platform technology for curing hitherto intractable human diseases, a potential which is exemplified by the availability of catalysts capable of cleaving biol