Provides a practical understanding of the unique and volatile physiology of the neonate and child,it fully examines the developmental changes which occur, which affect the response of numerous manipulations employed during by-pass, such as hypothermia, haemodilution, acid-base management, anticoagulation and anaesthesia. Jonas and Elliott are based at Boston s Children s Hospital and Great Ormond Street, London respectively, undoubtedly the most prestigious of units in this field worldwide and t